Written by a parent, not a doctor. Nothing here is medical advice.

Treatment protocols

The studies and protocols your team will mention, worked through in plain words: the pathways, the odds by risk group, what the study found and what it can't tell you about your kid. AALL1731 in full, AALL1732 in progress.

  1. Active, not recruiting

    AALL1731: the study behind your kid's roadmap

    If your kid has standard-risk B-cell acute lymphoblastic leukemia (B-ALL), you are going to hear “1731” a lot. It is the study that put blinatumomab, or blina, into standard treatment for children. Not every kid on the protocol gets blina, so I have laid out the different 1731 pathways and the numbers that go with each one. I found these figures hard to track down and understand. I hope having them together helps other parents. There are a lot of statistics here, but every child has their own journey. For a parent, the number that matters most is n=1: one child, your kid. These figures cannot tell you how your kid’s treatment will go, but they can help you understand the possibilities.

  2. RecruitingPlaceholder, not written yet

    AALL1732: the high-risk study

    This page is a placeholder. I have not started the real write-up of AALL1732 yet. If your kid has high-risk B-ALL, the roadmap may say “1732”: it is the Children's Oncology Group study asking whether adding inotuzumab ozogamicin to the usual chemotherapy keeps more kids in remission.